MYCi975
CAY-39622-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
2289691-01-4
Formulation
A solid
Purity
≥98%
MW
561,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
MYCi975 is an inhibitor of the protein-protein interaction between Myc and Myc-associated factor X (MAX).{68661} It binds to Myc (Kd = 2.75 µM) and increases GSK3β-mediated Myc phosphorylation in a cell-free assay. MYCi975 (5 and 10 µM) decreases the viability of MyC-CaP and LNCaP prostate cancer cells. It induces apoptosis in a panel of 11 breast cancer cell lines when used at a concentration of 10 µM.{68662} In vivo, MYCi975 (100 mg/kg) reduces tumor volume in a MyC-CaP mouse xenograft model.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
