Epigenetics Webinars from Active Motif
Stay up-to-date with the latest tips & techniques from epigenetics experts.
In this webinar, Dr. Rwik Sen, Field Application Scientist at Active Motif demonstrates how the PIXUL Multi-Sample Sonicator can be applied to generate fast, consistent, and high-throughput, sample preparation for use in multiomics research. Watch Webinar Now
In this webinar, Dr. Nick Pervolarakis, Computational Biologist at Active Motif provides a quick tutorial on how to use the UCSC Genome Browser to upload, analyze and view biological data sets for genomic bioinformatic analysis. Watch Webinar Now
In this webinar, Dr. Wayne Doyle, Bioinformatics Manager at Active Motif discusses the benefits of single cell, and multiomic analysis, how we utilize the 10X Genomics Multiome Kit technology, and why this approach is so powerful for genomics research. Watch Webinar Now
In this webinar, Dr. Benjamin Delatte, Group Leader, Advanced Research Lab at Active Motif discusses a newly developed and published technique, Anchor-Based Bisulfite Sequencing (ABBS) and the advantages it has for measuring DNA methylation on a genome-wide scale in comparison to traditional bisulfite based approaches. Watch Webinar Now
In this webinar, Dr. Michael Garbati, Product Manager - Epigenetic Services at Active Motif discusses the latest innovative, and novel variations of the CUT&Tag technique that now allows for translational research to be conducted on clinically relevant samples. Watch Webinar Now
Catch up on presentations from the first ever Chromatin-Con: Epigenetics & Human Disease Meeting 2021. Watch talks from international experts and their emerging research in the relationship between epigenetic mechanisms and human disease. The conference is structured into four sessions - two featuring speakers based in Europe, and two from speakers based in North America. Watch Now
In this webinar, Dr. Michael Garbati, Product Manager - Epigenetic Services at Active Motif talks about how the process of investigating chromatin has greatly improved with the recent innovation of techniques like CUT&RUN and CUT&Tag, which are faster and easier than traditional ChIP methods. Watch Webinar Now
In this webinar, Dr. Rupesh Kanchi Ravi, Director of Epigenetic Services at Active Motif, discusses how newly developed single-cell workflows, such as scATAC-Seq, and scRNA-Seq can be combined to create multiomic analysis of clinical samples, representing a major advancement from previous bulk analysis approaches. Watch Webinar Now
In this free webinar, Dr. Sarantis Chlamydas, Ph.D., Senior Market Development Manager at Active Motif, and Amit Sinha, Ph.D., CEO of Basepair Tech discuss the best ways to generate quality data using advanced, epigenomics techniques including CUT&Tag and ChIP-Seq, and then efficiently process and interpret epigenomic data using streamlined analysis pipelines. Watch Webinar Now
The 1st edition of the Cardio Epigenetics Chromatin Meeting is an online event that focuses on the emerging research into the relationship between epigenetic mechanisms and cardiovascular disease. Watch Webinar Now
In this free webinar, Dr. Joshua Messinger, Ph.D., R&D Scientist at Active Motif, describes how innovative PIXUL™ sonication technology fuels techniques allowing epigenetic analysis to be conducted on clinical samples - something which was previously very difficult to accomplish. Watch Webinar Now
ATAC-Seq is a powerful technique that enables the mapping of accessible, or open, chromatin regions across the genome. The ATAC-Seq assay has been used by many researchers to investigate the role of epigenetics in many biological processes and disease states. This webinar covers the ATAC-Seq method in depth and discusses how it can be applied to epigenetics research. Watch Webinar Now
The large amount of complex data generated by ChIP-Seq experiments makes bioinformatics analysis pipelines critical for successful ChIP-Seq projects. This webinar discusses some of the most popular bioinformatics tools and approaches to analyze ChIP-Seq data and provides an introduction to help you learn how to analyze ChIP-Seq data. Watch Webinar Now
ATAC-Seq and Single-Cell ATAC-Seq (scATAC-Seq) are powerful tools for investigating the epigenetic mechanisms responsible for regulating a particular cellular response or that contribute to a disease state. This webinar will explain how these popular techniques work and discuss how they can be useful in epigenetics research. Watch Webinar Now
Chromatin immunoprecipitation followed by next-generation sequencing (ChIP-Seq) is one of the most commonly used tools in epigenetics research. This webinar will discuss approaches to the technique of ChIP-Seq to help ensure a successful experiment. Watch Webinar Now
As scientists continue to learn more about the biology of aging, the role of epigenetics in regulating the aging process has become evident. In this webinar, Dr. Sarantis Chlamydas, Ph.D., Epigenetics Expert at Active Motif, discusses the epigenetic mechanisms involved in aging and highlights the available tools and strategies for studying these mechanisms. Watch Webinar Now
Epigenetic techniques have typically been difficult to use in a clinical setting. In this free webinar, Dr. Joshua Messinger, Ph.D., R&D Scientist at Active Motif discusses innovative approaches that have been developed to enable epigenetic analysis to be applied using clinical samples. Watch Webinar Now
Epigenetic tools and techniques provide a valuable avenue to understanding the underlying mechanisms of disease. In this webinar, Dr. Michael Garbati, Ph.D., Technical Support Scientist at Active Motif, discusses how epigenetic methods can be applied to study specific disease states, using the specific example of blood cancers including chronic lymphocytic leukemia (CLL). Watch Webinar Now
Achieving proper sonication of chromatin and DNA, from a wide array of sample types, is critical for the success of several of today’s most popular lab techniques. Limitations in traditional shearing approaches can lead to experimental failures and inconsistent results. Therefore, Active Motif has developed a new instrument to address those issues. In this webinar, Dr. Rwik Sen, Ph.D., Field Applications Scientist at Active Motif, discusses how the PIXUL™ Multi-Sample Sonicator addresses many of the issues around chromatin and DNA shearing. Watch Webinar Now
Aging results in a gradual and progressive loss of physiological functions and physical abilities over time. Overcoming the growing burden of age-related issues is one of the greatest challenges facing modern society. These issues are leading to a major drain on healthcare resources worldwide, so a better understanding of the biology of aging is critically important. In this webinar, Dr. Paul Shiels, Ph.D., Professor of Epigenetics at the University of Glasgow, discusses how our behavior and the environment impact health and aging at the molecular level. Watch Webinar Now
Traditionally, Histone PTM levels are measured by western blots or ELISAs, but these methods require large amounts of material and can only examine one histone modification at a time. In this webinar, Mary Anne Jelinek Ph.D., Senior Research Scientist at Active Motif will discuss our Histone H3 PTM Multiplex Assay and its advantages over traditional western blotting. Watch Webinar Now
Although ChIP-Seq has contributed greatly to our understanding of the epigenome and gene regulation, it is not without its limitations, which can impede our ability to answer complex scientific questions. In this webinar, Adam Blattler Ph.D., Research Scientist at Active Motif, will discuss the variety of tools and services we have developed to overcome many of these challenges. Watch Webinar Now
Mutations that lead to changes in gene expression are common in many human diseases. Therefore, a thorough understanding of the mechanisms regulating or mis-regulating gene expression is crucial to understanding disease initiation and progression. ChIP-Seq is the predominant method used to analyze DNA-protein interactions, but it can have limited resolution in identifying a transcription factor binding site. In this webinar, Bryce Alves, Ph.D., Research Scientist at Active Motif will discuss ChIP-Exo, a powerful technique for high-resolution mapping of transcription factor binding sites. Watch Webinar Now
An ongoing problem in ChIP-Seq data analysis is the often large discrepancy between expected changes in histone marks and the actual ChIP-Seq data when using drug-treated cells. In this webinar, Brian Egan, Ph.D., Epigenetic Services Manager at Active Motif, discusses a novel ChIP-Seq spike-in normalization strategy and shows how normalization of ChIP-Seq data using this approach reveals the expected changes in the final ChIP-Seq data set for inhibitor-treated samples. Watch Webinar Now
Chromatin Immunoprecipitation (ChIP) is a powerful tool for studying protein-DNA interactions, but it can be technically challenging. To date, ChIP studies have been mainly limited to cultured cells and model systems. In this webinar, Johanna Samuelsson, Ph.D., Sr. Research Scientist at Active Motif, discusses the pitfalls & challenges of generating high-quality ChIP data from difficult-to-ChIP samples, including primary cells, FFPE samples, and PBMCs. Watch Webinar Now
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In a growing number of people who contract COVID-19, symptoms persist long after the initial SARS-CoV-2 infection subsides. COVID-19 and long COVID patients display a variety of symptoms that reveal SARS-CoV-2’s versatility and its long-lasting impact on organ function. While this heterogeneity makes it difficult to study the disease, scientists apply every available technology to investigate the virus’ pathological mechanisms. In this webinar, Dr. Floyd Chilton, Director of the Precision Nutrition and Wellness Initiative at the University of Arizona, and Dr. Thomas Bumol, Executive Vice President and Director of the Allen Institute for Immunology, will discuss how they combine metabolomics, transcriptomics, and immune profiling to study SARS-CoV-2’s ability to attack multiple organs, even after the virus has been cleared from the body. Hosted by The Scientist.
Presented by Dr. Thierry Durand, Directeur de Recherche at the French National Center for Scientific Research (CNRS) and Head of the Department of Lipids at the Institute des Biomolécules Max Mousseron (IBMM). Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
Since lipids are involved in every major disease, it is impossible to overstate the importance of the use of lipid standards in their analysis as sentinels to monitor critical factors. Listen as Cayman scientist, Dr. Miguel Gijón, gives an overview of lipid biosynthetic pathways as well as a brief history of eicosanoid analysis. He also presents a typical workflow for eicosanoid analysis using LC-MS/MS, demonstrating the usefulness of lipid standards as well as recommendations for sample handling. Hosted as part of the 2021 LIPID MAPS® Spring School.
Cell death occurs for both physiological and pathological reasons. Varying modes of death are either programmed to safely remove healthy cells that are no longer useful or to stimulate an inflammatory response to clear cells that are useful but no longer healthy. Listen to Dr. Katie Parzych as she discusses the key morphological and biochemical hallmarks that can be used as markers to help distinguish the major types of cell death and explores the broad collection of assay kits, probes, antibodies, activators, and inhibitors available from Cayman that can be used to study the features of various cell death pathways. Do you have a question or comment for the presenter? Let us know.
The emergence of SARS-CoV-2 elicited a worldwide effort to discover new therapeutics and protective vaccines. Researchers are now accelerating the development of pandemic-relevant pharmaceutical drugs and vaccines at a record pace. This webinar will discuss therapeutic solutions to COVID-19 and delve into the highs and lows of developing pandemic drugs and vaccines at lightning speed. Hosted by Drug Discovery News.
Presented by Dr. Alan R. Brash, Professor of Pharmacology at Vanderbilt University. Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
The immuno-oncology field is a relatively new therapeutic avenue, and drugs targeting neoantigens, either directly or indirectly, have shown strong antitumor efficacy in the clinic. However, the identification of neoantigens and production of peptides are major bottlenecks in the development of personalized and universal cancer immunotherapies. Learn how these neoantigen epitopes can be identified and how peptides can be used during various stages in the development of therapeutics to generate more effective and durable treatments. Cayman’s immunopeptidome profiling techniques to discover neoantigen candidates through functional screening of MHC-bound neoepitopes is discussed. Key considerations in experimental design for optimal peptide identification are presented. Hosted by Nature Research in collaboration with GenScript.
Presented by Professor Edward Dennis, Chancellor I Chair and Distinguished Professor of Chemistry, Biochemistry, and Pharmacology at the University of California, San Diego, CA, USA. Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
Chemical probes are powerful tools to interrogate complex biological systems and have facilitated key discoveries that range from understanding how translation and basic cellular signaling processes work to developing targeted therapies. High-quality small molecule probes are complementary to commonly used genetic strategies and are central to basic and translational research. This webinar aims to provide researchers involved in developing and using chemical probes with practical suggestions to help select the most appropriate research tools along the path to amazing discoveries! Experts will also share how innovations using chemical probes are helping to enhance our understanding of complex disease pathways and mechanisms and accelerate translational efforts.
Presented by Dr. Maria Fedorova, a group leader at the Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, at the University of Leipzig. Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
Presented by Dr. Richard Gross, Director of the Division of Bioorganic Chemistry and Molecular Pharmacology and a Professor of Medicine, Chemistry and Developmental Biology at the Washington University School of Medicine campus and the Washington University Danforth campus. Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
Presented by Dr. Bruce Freeman, Irwin Fridovich Distinguished Professor and Chair of the Department of Pharmacology and Chemical Biology at the University of Pittsburgh. Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
Harnessing the immune system to treat cancer is a relatively new therapeutic avenue, and therapies that target neoantigens, either directly or indirectly, have shown strong antitumor efficacy in select patients. The goal is to find ways to help more patients benefit from these revolutionary treatments. Listen to Dr. Julie Rumble discuss some of the key considerations for planning your immunopeptidome profiling experiment, from antibody choice to biological input and mass spec output. Optimization of these experiments will help to drive better peptide sequencing and increased neoantigen identification. Immunopeptidome profiling of MHC can be a powerful tool for empirically determining what peptides may be presented as possible targets for immune-mediated tumor destruction. Hosted by Hanson Wade as part of the 5th Annual Neoantigen Based Therapies Summit.
The Seahorse XF Analyzer is an important and powerful tool used for measuring cellular bioenergetics. Listen to Dr. David Hoffman explore how it works and how Cayman utilizes this technology to optimize its extracellular flux assays to determine mitochondrial function in cellular systems. Learn more about our Contract Services including our Cellular Metabolism Services.
Presented by Professor Emeritus Robert "Bob" Murphy, Distinguished Professor Emeritus, Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO. Hosted by LIPID MAPS® as part of the LIPID MAPS® Webinar Series.
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