Protriptyline (hydrochloride)
CAY-31179-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
1225-55-4
Formulation
A solid
Purity
≥98%
MW
299,8
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A tricyclic antidepressant; binds to the norepinephrine and 5-HT transporters (Kd = 1.41 and 19.6 nM, respectively); binds to histamine H1, muscarinic acetylcholine, and α1-adrenergic receptors (Kds = 25, 25, and 130 nM, respectively); inhibits norepinephrine uptake into rat whole brain and hypothalamic synaptosomes (IC50s = 12 and 0.55 μM, respectively) and 5-HT uptake into rat whole brain synaptosomes (IC50 = 5.5 μM); inhibits food-induced cataplexy in narcoleptic dogs at 1 mg/kg, i.v.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
