Pridopidine
CAY-38302-10 10 mg
CAS
346688-38-8
Formulation
A solid
Purity
≥95%
MW
281,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A σ1 receptor ligand and dopaminergic stabilizer; binds to the σ1 receptor and dopamine D2 receptor in the high-affinity state (Kis = 81.3 and 7,521 nM, respectively); increases striatal DOPAC levels and locomotor activity, as well as inhibits amphetamine-induced locomotor activity, in rats at 100 µmol/kg; improves motor function and reduces striatal mHtt aggregates in the R6/2 mouse model of Huntington’s disease at 5 or 6 mg/kg; prevents muscle atrophy and the loss of innervated neuromuscular junctions in the SOD1-G93A mouse model of ALS at 30 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
