CAS
1311174-68-1
Formulation
A solid
Purity
≥98%
MW
491,58222
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of ApoE4 domain interactions (IC50 = 116 nM in a FRET reporter assay for amino- and carboxy-terminal domain interactions); restores intracellular trafficking of ApoE4 to the endoplasmic reticulum and Golgi apparatus in Neuro-2a cells expressing EGFP-ApoE4 or EGFP-ApoE4-R61T at 100 nM; restores levels of mitochondrial complex IV subunit 1 in Neuro-2a cells expressing ApoE4 (EC50 = 39 nM) and increases mitochondrial motility in neurons expressing ApoE4 (EC50 = <1 nM)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).