Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

ML-364

  CAY-21774-5 5 mg


Data Sheet:     SDS:    

CAS
1991986-30-1  

Formulation
A crystalline solid  

Purity
≥98%  

MW
517,5  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
An inhibitor of USP2 (IC50 = 1.1 µM); inhibits the closely related USP8 (IC50 = 0.95 µM); no activity at multiple proteases or 102 kinases, including cell cycle regulators; increases cyclin D1 degradation in HCT116 cells; induces cell cycle arrest at the G1 phase in Mino and HCT116 cells; inhibits proliferation of HCT116 cells (IC50 = 3.6 µM); decreases homologous recombination-mediated DNA repair in DR-GFP U2OS cells
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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