CAS
1991986-30-1
Formulation
A crystalline solid
Purity
≥98%
MW
517,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of USP2 (IC50 = 1.1 µM); inhibits the closely related USP8 (IC50 = 0.95 µM); no activity at multiple proteases or 102 kinases, including cell cycle regulators; increases cyclin D1 degradation in HCT116 cells; induces cell cycle arrest at the G1 phase in Mino and HCT116 cells; inhibits proliferation of HCT116 cells (IC50 = 3.6 µM); decreases homologous recombination-mediated DNA repair in DR-GFP U2OS cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).