KL1333
CAY-39670-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1800405-30-4
Formulation
A solid
Purity
≥98%
MW
240,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An NQO1 substrate and a derivative of β-lapachone; converted by NQO1 to NAD+ and increases the ratio of NAD+ to NADH in a cell-free assay, as well as C2C12 and L6 myoblasts, at 1, 1, or 2 µM, respectively; increases intracellular ATP levels, as well as decreases intracellular lactate and ROS levels, in primary fibroblasts isolated from patients with MELAS at 1 µM; increases the levels of mitochondrial complex I and mitochondrial complex III, as well as increases the OCR, in primary fibroblasts isolated from patients with MELAS at 1 µM; inhibits cisplatin-induced apoptosis, production of mitochondrial ROS, and mitochondrial membrane depolarization in primary mouse cochlear organ of Corti cells at 1 µM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
