Bobcat 339
CAY-31453-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
2280037-51-4
Formulation
A crystalline solid
Purity
≥98%
MW
297,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Bobcat 339 is a cytosine derivative that was originally found to be an inhibitor of ten-eleven translocation methylcytosine dioxygenase 1 (TET1) and TET2 (IC50s = 33 and 73 µM, respectively, in cell-free assays).{61034} However, it was found that the TET inhibitory activity was due to residual copper in the Bobcat 339 preparation used for the experiments.{65280} Copper-containing Bobcat 339 (10 µM) also reduces DNA 5-hydroxymethylcytosine (5-hmC) levels in HT22 hippocampal neurons, but copper-free preparations of Bobcat 339 (50 µM) do not reduce DNA 5-hmC levels in Hep3B cells.{61034,65280}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
