Bentamapimod
CAY-21482-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
848344-36-5
Formulation
A crystalline solid
Purity
≥98%
MW
457,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Bentamapimod is an orally bioavailable inhibitor of Jun kinases (JNKs), with IC50 values for JNK1, JNK2, and JNK3 of 80, 90, and 230 nM, respectively.{33921,33920} It is selective for JNKs over a panel of 25 related kinases.{33921} Bentamapimod induces regression of endometriotic lesions without suppressing estrogen action in animal models of endometriosis.{33922,33924} It blocks proliferation and induces apoptosis of T cells in vitro and inhibits cancer stem cell survival, self-renewal, and tumor-initiating capacity in vitro and in mice.{33920,33923}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
