4-IPP
CAY-31770-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
41270-96-6
Formulation
A solid
Purity
≥98%
MW
282,1
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
4-IPP is an inhibitor of macrophage migration inhibitory factor (MIF).{59363} It acts as a suicide substrate for MIF, leading to covalent modification of the N-terminal proline required for activation of its catalytic activity. 4-IPP (10 and 100 µM) inhibits the migration and anchorage-independent growth of A549 non-small cell lung cancer (NSCLC) cells. It inhibits proliferation of, and induces apoptosis in, TPC-1 thyroid carcinoma cells when used at concentrations of 50 and 100 µM.{59364} 4-IPP (~50 mg/kg) also inhibits the tautomerase activity of MIF in mouse liver in vivo.{59363}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
