Epigenetics & Chromatin

The field of epigenetics involves the study of chromatin-based phenomena and heritable changes in gene expression not resulting from changes in gene structure or sequence. DNA is wrapped around an octamer of histone proteins to form chromatin, then packaged into chromosomes by other structural proteins. The organization of genetic material in the nucleus has profound effects on all processes that require access to DNA. Much of the regulation of the genome involves histone modifications (e.g. acetylation, methylation, phosphorylation) and DNA methylation at CpG islands that regulated a myriad of signals that are critical to cell function.     

	Active Motif Antibodies Catalog Scarica PDF		CUT&Tag Assay KIt Validated Antibodies Scarica PDF
	Epigenetics Research Tools - Cayman    Scarica PDF		Active Motif ATAC-Seq Scarica PDF
	DNA Methylation Products and Services Scarica PDF		The ChIP Assay Experts™ and ChIP Kit Selection Guide Active Motif Scarica PDF ChIP & Specialty ChIP Kits Antibodies Accessories Sonicator
	Epigenetics - BPS Scarica PDF		Recombinant Proteins for Epigenetic Research  Scarica PDF
	MotifVations Cancer Epigenetics Active Motif - Scarica PDF		Active Motif Epigenetic Drug Discovery Scarica PDF TOOLS FOR EPIGENETIC DRUG DISCOVERY  Proteins Nucleosomes Antibodies Assays Services
	Reagents and Kits for Analysis of Protein-DNA Interactions Scarica PDF		Custom Services Active Motif Scarica PDF • ATAC-Seq • ChIP-Seq • DNA Methylation • Gene Regulation • Histone Analysis
	Epigenetics -  Product and Services Active Motif Scarica PDF		Tools for Disease Research Targeting Epigenetics & Gene Regulation Scarica PDF
	Active Motif Sonication Scarica PDF		SAM-Screener™ Assay Kits Scarica PDF Screen for SAM (S-adenosyl-L-methionine) competitive methyltransferase inhibitors with SAM-Screener™ one-step, fluorescence polarization assays. Assay kits available for the following enzymes: ° SET7/9 (Item No. 600490) ° GLP (Item No. 600570) ° MLL1 (Item No. 600580)
	Active Motif TransAM® Transcription Factor ELISAs TransAM® Transcription Factor Assays are DNA-binding ELISAs that facilitate the study of transcription factor activation in mammalian tissue and cell extracts. With assays available for over 40 different targets and over 800 papers citing their use, TransAM Kits have become the method of choice for detecting and quantifying activated transcription factors. Scarica PDF		Active Motif LightSwitch™ Luciferase  Assay System The LightSwitch™ Luciferase Assay System includes over 18,000 promoters that have been cloned from the human genome into transfection-ready LightSwitch reporter vectors, which are assayed in living cells using our optimized luciferase assay reagents and protocols. Also available are Synthetic Response Element constructs and Pathway Reporter Stable Cell Lines. Scarica PDF