CAY-31530-50
For screening a variety of anti-inflammatory compounds; contains ~235 compounds in a 96-well Matrix™ tube rack format as 10 mM stock solutions in DMSO; includes a variety of compounds that inhibit pro-inflammatory cytokine production, macrophage and T cell activation, cytokine storm receptor signaling, the NLRP3 inflammasome, NF-κB signaling, kinases, and inflammatory lipid mediator production and metabolism; also includes corticosteroids, glucocorticoids, and inhibitors of NETosis, coagulation, and platelet aggregation.
CAY-30390-50
For screening a variety of antiviral-associated compounds; contains >410 antiviral-associated compounds in a 96-well Matrix™ tube rack format as 10 mM stock solutions in DMSO; includes a variety of compounds with antiviral activity against HIV, HBV, HCV, influenza, HSV, and coronaviruses, among others, as well as several compounds with antimalarial activity; molecular targets include HIV reverse transcriptase, protease, and integrase, RNA-dependent RNA polymerases, and HCV NS proteins
CAY-23537-50
For screening a variety of autophagy-associated compounds; contains more than 150 autophagy-associated compounds as 10 mM stock solutions in DMSO; includes a variety of inhibitors and inducers of autophagy, including but not limited to, mTOR, PI3K, LRRK2, and Aurora kinase inhibitors, HDAC inhibitors, protease inhibitors, calcium channel blockers, p53 and AMPK modulators, and Vps34 inhibitors
CAY-10506-50
The Bio-Active Lipid I Screening Library consists of 11 plates and contains more than 800 compounds in a 96-well Matrix™ tube rack format as 1.0 mM stocks in DMSO. The library may include prostaglandins, thromboxanes, cannabinoids, D-myo-inositol-phosphates, phosphatidylinositol-phosphates, sphingolipids, inhibitors, receptor agonists and antagonists, ceramide derivatives, and several other complex polyunsaturated fatty acids. This library collection is ideal for prostanoid or other G protein-coupled receptor screening, target validation, secondary screening, validating new assays and for routine pharmacological applications.
CAY-10507-50
The Bio-Active Lipid II Screening Library consists of 3 plates and contains more than 190 compounds in a 96-well Matrix tube rack format as 0.1 mM stocks in DMSO. The library may include prostaglandins, isoprostanes, thromboxanes, leukotrienes, lipoxins and several other complex polyunsaturated fatty acids. This library collection is ideal for prostanoid or other G protein-coupled receptor screening, target validation, secondary screening, validating new assays and for routine pharmacological applications.
CAY-28940-50
For screening of a variety of kinase inhibitors; contains ~869 selective and non-selective kinase inhibitors in a 96-well Matrix™ tube rack format as 10 mM stock solutions in DMSO; includes inhibitors of a wide range of lipid, receptor and non-receptor tyrosine, serine/threonine, and dual specificity kinases including those belonging to ROCK, ALK, GSK3, PKC, PDGFR, VEGFR, Src, MAPK, CDK, and PI3K families; has greater coverage of individual kinases, kinase isoforms and mutants, and kinase families compared to Cayman's Kinase Screening Library
CAY-11076-50
The Epigenetics Screening Library contains more than 140 small molecules that are known to modulate the activity of a variety of epigenetic 'writers and erasers' and “reader” proteins in a 96-well Matrix tube rack format as 10 mM stocks in DMSO. It may include compounds that modulate the activity of methyltransferases, demethylases, histone acetyltransferases, histone deacetylases, and acetylated histone binding proteins.
CAY-10504-50
The Fatty Acid Screening Library contains more than 75 compounds of fatty acids with diverse biological activities in a 96-well Matrix tube rack format as 10 mM stocks in DMSO. The library may also include some of the most commonly-ordered fatty acids, including arachidonic, linoleic, eicosapentaenoic, stearic, α- and γ-linolenic, oleic, and palmitic acids. As well as some unusual fatty acids, including 9-thiastearic acid, 2-hydroxymyristic acid, AUDA, and CUDA may be included.
CAY-23538-50
For screening FDA-approved drugs; contains ~875 compounds as 10 mM stock solutions in DMSO; contains antidiabetic, antiseizure, antipsychotic, antibiotic, and antiviral agents, non-steroidal anti-inflammatory drugs (NSAIDs), and chemotherapeutics, among others
CAY-28760-50
For screening a variety of immuno-oncology associated compounds; contains more than 90 cancer and immunology-associated compounds as 10 mM stock solutions in DMSO; includes a variety of immuno-oncology target modulators, including but not limited to, adenosine, CCR, CXCR, and TLR agonists and antagonists, BTK, PI3K, and BRAF inhibitors, PD-1/PD-L1 interaction inhibitors, and HDAC inhibitors
CAY-10505-50
For screening of a variety of kinase inhibitors; contains ~160 selective and non-selective kinase inhibitors as 10 mM stock solutions in DMSO; includes inhibitors of a wide range of lipid, receptor and non-receptor tyrosine, serine/threonine, and dual specificity kinases including those belonging to the ROCK, ALK, GSK3, PKC, PDGFR, VEGFR, Src, MAPK, CDK, and PI3K families; targets more than 70 distinct kinases and kinase families, as well as numerous additional kinase isoforms and individual kinases within target families
CAY-10501-50
The Prostaglandin Screening Library I contains more than 70 “F-series” of prostaglandins and isoprostanes in a 96-well Matrix™ tube rack format as 2 mM stocks in DMSO.
CAY-10502-50
The Prostaglandin Screening Library II contains more than 60 “D and E-series” of prostaglandins in a 96-well Stability data is not available for individual compounds as supplied in the screening library. Panels are routinely re-evaluated to include new catalog introductions as the research evolves.
CAY-10503-50
The Prostaglandin Screening Library III contains more than 70 “A and J-series” of prostaglandins in a 96-well Matrix tube rack format as 2 mM stocks in DMSO. The library may also include thromboxanes, lactones, stable PGH, prostacyclin mimic, metabolites, and potent PGA and PGJ analogs.
CAY-9001827-50
This small molecule library contains molecules that are known either to induce differentiation, to maintain self-renewal and proliferation, or to improve the reprogramming efficiency of various stem cell populations.
CAY-9003370-50
For screening a variety of terpenes; contains ~95 terpenes in a 96-well Matrix™ tube rack format as 10 mM stock solutions in DMSO; contains a diverse group of natural products with assorted biological activities and structural variety ranging from simple monocyclic compounds, such as (±)-limonene, to complex multicyclic structures, such as that of paxillene