von Willebrand Factor Antibody / vWF
NSJ-V3491IHC-7ML 7 ml
Data Sheet: 
Reactivity
Human
Applications
IHC-P
Source / Host
Rabbit
Immunogen
Amino acids 1815-1939 from the human protein were used as the immunogen for this recombinant vWF antibody.
Clone
VWF/1859R
Purity
Protein A affinity chromatography
Long Term Storage
Store the recombinant vWF antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Description
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
