anti-Nitrotryptophan (NW), mAb (117C)
JAI-MNW-020P 20 µg
Data Sheet: 
Reactivity
All, Human
Applications
IHC, WB
Specificity
Recognizes 6-Nitrotryptophan.
Clone
117C
Purity
Protein A purified.
Shipment
BLUE ICE
Short Term Storage
+4°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 3 years after receipt when stored at -20°C.
Description
Monoclonal Antibody. Recognizes 6-Nitrotryptophan. Lyophilized. Contains 10mM PBS (pH 7.4). Reactive nitrogen species (RNS) are formed in a variety of diseases such as atherosclerosis, inflammation, cancer and neurodegenerative diseases. Peroxinitrite (ONOO-) is known as a potent biological oxidant, which is formed via very fast reaction between nitric oxide (NO) and superoxide (O2-). Peroxinitrite can induce nitration of aromatic amino acids such as Tyr, Trp, Phe and His, which results in modulation of protein functions. To date, 6-nitrotryptophan (6-NO2-Trp) is shown to be one of the most stable and major peroxynitrite-modified amino acids, and growing evidences suggest that nitrotryptophan may play a significant role in the cellular regulation under nitrosative stress. This antibody is suitable for immunohistochemistry, western blotting and ELISA and may provide a powerful tool for the investigation of nitrosative stress inside living bodies.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
