CAS
146709-78-6
Formulation
A solid
Purity
≥98%
MW
474,98512
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An AT1 receptor antagonist (IC50 = 3.3 nM); inhibits angiotensin II-induced pressor responses in conscious normotensive rats; decreases mean arterial pressure in conscious spontaneously hypertensive rats at 1.082 µmol/kg; improves motor nerve conduction velocity in the sciatic nerve in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg in the drinking water; decreases disease severity and NF-κB and AP-1 activation in a mouse model of LPS-induced acute lung injury at 10 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).