CAS
448947-81-7
Formulation
A crystalline solid
Purity
≥98%
MW
355,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A Piezo1 channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively); selective for Piezo1 as it elicits Ca2+ flux in Piezo1- but not Piezo2-transfected HEK293T cells; slows the inactivation phase of murine Piezo1 transient currents and sensitizes them to activation by mechanical pressure; induces dehydration and a change in shape of wild-type red blood cells but not Piezo1 knockout cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).