Y-33075 (hydrochloride)
CAY-36216-1 1 mg
Data Sheet: 
CAS
471843-75-1
Formulation
A solid
Purity
≥98%
MW
316,78524
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of ROCK2 (IC50 = 3.6 nM); selective for ROCK2 over PKC and CaMKII (IC50s = 420 and 810 nM, respectively); topical application reduces intraocular pressure in rabbit and cynomolgus monkeys at 0.05% v/v; increases axonal regeneration at the crush site in a cat model of surgically-induced optic nerve damage at 10 and 100 µM; inhibits demyelination and reduces the incidence of relapse episodes in a mouse model of chronic relapsing EAE
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
