CAS
947669-91-2
Formulation
A crystalline solid
Purity
≥97%
MW
437,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A selective inhibitor of ABHD6 (IC50 = 70 nM); increases Ucp1 expression and the OCR in differentiated 3T3-L1 mouse adipocytes at 10 µM; increases the expression of Ucp1, Prdm16, Tmem26, and Tbx1 in visceral adipose tissue in mice fed a high-fat diet at 10 mg/kg per day; reduces adipose tissue mass and prevents glucose-intolerance and increases in body weight in mice fed a high-fat diet; increases brain levels of 2-AG and decreases EAE severity in wild-type, but not CB2 receptor knockout, mice at 10 mg/kg per day starting at disease onset
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).