CAS
1160247-92-6
Formulation
A solid
Purity
≥98%
MW
351,276729
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A muscarinic M5 receptor positive allosteric modulator (EC50 = 1.16 µM in a calcium mobilization assay); selective for M5 mAChRs over M1, M2, M3, and M4 mAChRs in CHO cells expressing the human receptors (EC50s = >30 µM for all in calcium mobilization assays); reduces DOI-induced head-twitch behavior in mice at 10 mg/kg; reverses MK-801-induced memory deficits in the novel object recognition test in mice when administered alone or in combination with GS-39783
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).