VU0155041 (sodium salt)
CAY-21775-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1259372-69-4
Formulation
A crystalline solid
Purity
≥98%
MW
338,16107
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A selective positive allosteric modulator of mGluR4 (EC50 = 2.5 μM in a thallium flux assay); has no effect on radioligand binding at 67 G protein-coupled receptors, ion channels, and transporters; lacks antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 μM; decreases haloperidol-induced catalepsy and reverses reserpine-induced askinesias in rat models of Parkinson’s disease; restores social behavior in the Oprm-/- mouse model of autism; decreases anxiety-like behavior in the elevated plus maze in mice
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
