Uroplakin 1B Antibody / UPK1B
NSJ-V8152-100UG 100 ug
Data Sheet: 
Reactivity
Human
Applications
IHC-P
Source / Host
Mouse
Immunogen
A recombinant human partial protein (amino acids 109-229) was used at the immunogen for this UPK1B antibody.
Clone
UPK1B/3081
Purity
Protein G affinity chromatography
Long Term Storage
Store the UPK1B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
