Trehalose 6,6'-Dibehenate
CAY-37911-1 1 mg
Synonyms: 22:0 Trehalose|TDB|Trehalose Dibehenate
Data Sheet: 
SDS:
SDS:
CAS
66758-35-8
Formulation
A solid
Purity
≥95%
MW
987,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Trehalose 6,6'-dibehenate (TDB) is a synthetic glycolipid and derivative of trehalose-6,6′ dimycolate (TDM), also known as mycobacterial cord factor.{68365} It binds to a fusion protein of mouse macrophage-inducible C-type lectin (Mincle) and human IgG1 Fc in a cell-free assay when used at a concentration of 10 µg/ml. TDB (5 µg/ml) induces nitric oxide (NO) and G-CSF production in mouse bone marrow macrophages in a Mincle-dependent manner. Liposomes containing TDB and dimethyldioctadecylammonium (DDA; Item No. 26120) as adjuvants and the mycobacterial lipid antigens diacylated sulfoglycolipid (Ac2SGL) and phosphatidyl-myo-inositol dimannoside (PIM2) decrease spleen bacterial load and the number of lung and spleen lesions in a guinea pig model of M. tuberculosis infection.{36983}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
