Synonyms: D-α-Tocopheryl Polyethylene Glycol Succinate|Tocophersolan|TPGS|TPGS 1000|VE-TPGS|Vitamin E TPGS
CAS
9002-96-4
Formulation
A solid
Purity
≥80%
MW
574,8
Shipment
-20
Long Term Storage
-20
Description
A nonionic surfactant; CMC = 0.02 mM at room temperature; inhibits P-gp substrate-induced ATPase activity in cell-free assays (IC50s = 0.4-3.25 µM); reverses benzo[a]pyrene-induced locomotor deficits in zebrafish larvae at 1 µM; intravenous administration of nanocrystals containing tocofersolan (50 mg/kg) and paclitaxel reduces tumor growth in an NCI/ADR-RES mouse xenograft model; liposomes containing tocofersolan and DOTMA and encapsulating anti-miR-21 accumulate in the liver, lung, and spleen and decrease lung fibrosis in a mouse model of bleomycin-induced pulmonary fibrosis
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).