Synonyms: Scutellarein tetramethyl ether; 5-Methoxysalvigenin; 4',5,6,7-Tetramethoxyflavone; NSC53908


Source / Host
Plant
CAS
1168-42-9
Purity
>95% (HPLC)
MW
342.3
Shipment
Ambient
Short Term Storage
-20°C
Long Term Storage
-20°C
Shelf Life
Stable for at least 2 years after receipt when stored at -20°C.
Description
Chemical. CAS: 1168-42-9. Formula: C19H18O6. MW: 342.3. Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-kappaB pathway. It suppressed IkappaB kinase complex alpha/beta (IKKalpha/beta) and Inhibitory-kappa-B-alpha (IkappaBalpha), inhibiting p65 translocation and thereby suppressing COX-2 and iNOS expression. This compound is modulating bacterial resistance to antimicrobial drugs most probably via efflux pump inhibition. It also showed anti-mutagenic activity.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).