SU 6668
CAY-13873-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
252916-29-3
Formulation
A crystalline solid
Purity
≥98%
MW
310,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
SU 6668 is an inhibitor of the receptor tyrosine kinases PDGFRβ, VEGFR2, and FGFR1 (IC50 = 0.06, 2.4, and 3.0 μM, respectively) but not EGFR (IC50 >100 μM).{21720,21717} Through these actions, SU 6668 suppresses tumor growth, blocks angiogenesis in tumors, and induces apoptosis of tumor vasculature and regression of established tumors.{21718,21716,21719} It also inhibits metastasis in a mouse orthotopic model of melanoma.{21715} SU 6668 also inhibits Aurora kinases B and C (IC50 = 35 and 210 nM, respectively) and may target other kinases.{21738,17331}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
