Ro 08-2750
CAY-28772-5 5 mg
Data Sheet: 
CAS
37854-59-4
Formulation
A solid
Purity
≥95%
MW
270,24366
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A p75NTR ligand; completely inhibits NGF binding to p75NTR in PC12 cells at 100 μM; binds to NGF dimers (Kd = ~1 μM) to induce a conformational change that prevents NGF binding to p75NTR or TrkA; inhibits NGF-induced death of SK-N-MC cells and inhibits autophosphorylation of TrkA in PC12 cells; reverses NGF-induced decreases in β-catenin mRNA expression in, and migration of, SKOV3 and OVCAR-3 ovarian cancer cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
