Retinyl Acetate
CAY-20242-10 10 g
Synonyms: NSC 122045|NSC 122760|Ro 1-5275|Vitamin A Acetate
Data Sheet: 
SDS:
SDS:
CAS
127-47-9
Formulation
A semi-solid
Purity
≥98%
MW
328,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Retinyl acetate is a natural form of vitamin A (Item No. 20241).{51437} It inhibits ascorbic acid- or ferrous sulfate-induced increases in malondialdehyde (MDA) levels in rat brain mitochondria when used at a concentration of 100 µM.{51438} Retinyl acetate binds to retinol-binding protein (Kd = 220 nM for the human protein) and inhibits organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3 in CHO cells expressing the human transporters (Kis = 1.22 and 3.89, respectively).{51439,48817} It inhibits the formation of mammary adenocarcinomas induced by the polycyclic aromatic hydrocarbon 7,12-dimethylbenz[a]anthracene (DMBA; Item No. 30383) in rats when administered at a dose of 2.5 mg/animal.{51441} Retinyl acetate (352 µmol/kg) is teratogenic to rat fetuses when administered to pregnant dams.{51440} Formulations containing retinyl acetate have been used as skin-conditioning agents in cosmetics.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
