Radiprodil
CAY-29712-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
496054-87-6
Formulation
A solid
Purity
≥98%
MW
397,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Radiprodil is an antagonist of NR2B subunit-containing NMDA receptors (IC50 = 8 nM).{52284} It is selective for NR2B subunit-containing NMDA receptors over NR1 and NR2A subunit-containing NMDA receptors at 15 µM. Radiprodil (10 nM) reduces amyloid β (1-42) (Aβ42) and Aβ40-induced decreases in dendritic spine density in mouse hippocampal CA1 pyramidal neurons.{52285} Radiprodil (2 mg/kg) restores novel object-stimulated locomotion in a marmoset model of MPTP-induced Parkinson's disease.{47789}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
