
Reactivity
Human
Specificity
Detects human RBP4. Does not cross-react with human adiponectin, human resistin or human RELM-beta.
Sample Type
Cell Culture Supernatant, Plasma, Serum, Urine
Assay Range
0.001 to 5µg/ml
Sensitivity
1ng/ml
Shipment
BI
Short Term Storage
+4°C
Long Term Storage
+4°C
Shelf Life
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
Description
ELISA Assay. Detects human RBP4. Does not cross-react with human adiponectin, human resistin or human RELM-beta. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum, Urine. Range: 0.001 to 5µg/ml. Sensitivity: 1ng/ml. Retinol binding protein 4 (RBP4; RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function and recent studies have shown an association between serum RBP4 levels and urinary albumin excretion. The urinary RBP4 concentration may be a valuable marker for both, insulin resistance and microalbuminuria in insulin-resistant subjects.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).