CAS
1798331-92-6
Formulation
A solid
Purity
≥98%
MW
300,7
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
QX-77 is an activator of chaperone-mediated autophagy (CMA).{48935} It decreases mouse embryonic fibroblast (MEF) and Neuro2a cell death induced by paraquat or oleic acid (Item Nos. 90260 | 24659). QX-77 (20 µM) rescues defective trafficking and lysosomal localization of the CMA receptor LAMP2A in Ctns-/- MEFs and CTNS knockout human proximal tubule cells, models of the lysosomal storage disorder cystinosis.{48936}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).