Pyrithiamine (hydrobromide)
CAY-19526-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
534-64-5
Formulation
A solid
Purity
≥95%
MW
420,1
Shipment
-20
Long Term Storage
-20
Shelf Life
730
Description
Pyrithiamine is the pyridine analog of thiamine that prevents growth of organisms that require intact thiamine.{35137} It inhibits the growth of bacterial and fungal species at a pyrithiamine:thiamine ratio of 10:1 in growth media and induces symptoms of thiamine deficiency in mice at a dietary ratio of 3:1. These effects are reversible with addition of sufficient thiamine in all species. Pyrithiamine inhibits the formation of cocarboxylase from thiamine in chicken blood in a dose-dependent manner.{35139} It has been used to induce thiamine deficiency in various disease models, including rat models of alcoholism and diencephalic amnesia, to study the effects of thiamine deficiency on disease pathology.{35141,35143}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
