Progranulin (mouse) ELISA Kit
AG-45A-0019YEK-KI01 96 wells
Data Sheet: 
Manual:
SDS:
Manual:
SDS:
Reactivity
Mouse
Specificity
Detects mouse progranulin. Does not cross-react with human progranulin.
Sample Type
Cell Culture Supernatant, Serum
Assay Range
0.125 to 8ng/ml
Sensitivity
60pg/ml
Shipment
BI
Short Term Storage
+4°C
Long Term Storage
+4°C
Shelf Life
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
Description
ELISA Assay. Detects mouse progranulin. Does not cross-react with human progranulin. Colorimetric assay. Sample Types: Cell Culture Supernatant, Serum. Range: 0.125 to 8ng/ml. Sensitivity: 60pg/ml. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer‘s disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
