Synonyms: (+)-Catechin-(4α→8)-(+)-catechin|Proanthocyanidin B3|Procyanidol B3


CAS
23567-23-9
Formulation
A crystalline solid
Purity
≥98%
MW
578,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A polyphenol flavonoid dimer with diverse biological activities; inhibits Aβ42 aggregation (IC50 = 3.54 μM); destabilizes preformed Aβ42 fibrils (EC50 = 5.12 μM); reduces oxidation of linoleic acid and scavenges DPPH free radicals in cell free assays at 1 mM; inhibits hydrogen peroxide-induced production of iNOS and apoptosis in primary murine chondrocytes; reduces chondrocyte apoptosis, pseudocapsule thickness, and the frequency of ectopic cartilage formation in a mouse model of surgically induced osteoarthritis at 0.01 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).