CAS
18836-52-7
Formulation
A crystalline solid
Purity
≥95%
MW
223,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An amide alkaloid; cytotoxic to HL-60 and MCF-7 cancer cells (IC50s = 13 and 1.8 µg/ml, respectively); inhibits HMGB1-induced TNF-α, IL-1α, and IL-1β production and ERK1/2 phosphorylation in HUVECs at 10 and 20 µM; prolongs survival time in a HMGB1-induced mouse model of sepsis at 9 µg/animal
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).