
CAS
937272-79-2
Formulation
A crystalline solid
Purity
≥98%
MW
472,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of both FLT3 and JAK2 (IC50s = 22 and 23 nM, respectively); blocks the activities of the FLT3 D835Y mutant, FLT3 with ITDs, and JAK2 with a V617F substitution (IC50s = 6, 20-180, and 220 nM, respectively); orally bioavailable, inhibiting tumor growth and metastasis in xenografts in mice
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).