PQR530
CAY-28563-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1927857-61-1
Formulation
A crystalline solid
Purity
≥98%
MW
407,418006
Shipment
-20
Long Term Storage
-20
Shelf Life
730
Description
A dual inhibitor of PI3Kα and mTOR (IC50s = 11.1 and 7.4 nM, respectively); inhibits phosphorylation of Akt and ribosomal S6 kinase in A2058 melanoma cells (IC50s = 62.2 and 61.1 nM, respectively); inhibits cell growth in a panel of 66 cancer cell lines (mean GI50 = 0.43 µM); reduces tumor growth in an OVCAR-3 mouse xenograft model at 25 mg/kg; decreases the number of seizures per week in a Tsc1GFAP conditional knockout mouse model of epilepsy
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
