Synonyms: CFTR Inhibitor IV|Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor IV


CAS
931706-15-9
Formulation
A crystalline solid
Purity
≥95%
MW
438,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A cell-permeable pyrimido-pyrrolo-quinoxalinedione that reversibly inhibits CFTR chloride channels (IC50 = 90 nM); reduces the size and number of renal cysts in a neonatal kidney organ culture model of polycystic kidney disease; increases VEGF-A production in cultured airway epithelial NCI-H292 cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).