PLX7904
CAY-20710-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1393465-84-3
Formulation
A crystalline solid
Purity
≥98%
MW
512,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A RAF inhibitor (IC50s = 2.4, 140, and 91 nM for mutant B-RAFV600E, wild-type B-RAF, and C-RAF, respectively); inhibits phosphorylation of ERK in A375 and COLO 829 cells (IC50s = 16 and 18 nM, respectively); does not induce paradoxical pERK activation and proliferation of cancer cell lines (EC50s = >200 μM); inhibits tumor growth in a mouse COLO 205 colon cancer xenograft model
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
