PF-05175157
CAY-21778-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1301214-47-0
Formulation
A crystalline solid
Purity
≥98%
MW
405,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of ACC1 and 2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively); inhibits formation of malonyl-CoA in primary rat hepatocytes (EC50 = 29.9 nM); inhibits formation of malonyl-CoA in the liver and skeletal muscle, inhibits hepatic de novo lipogenesis, and lowers the respiratory exchange rate in rats (ED50s = 6, 11, 7.8, and 3.5 mg/kg, respectively)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
