PD 089828
CAY-21435-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
179343-17-0
Formulation
A solid
Purity
≥98%
MW
405,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of EGFR, PDGFβ, FGF, and c-Src (IC50s = 0.15, 1.76, 5.47, and 0.18 µM, respectively); inhibits MAPK (IC50 = 7.1 µM); selective over insulin receptor tyrosine kinase, PKC, and CDK4 (IC50s = >50 µM); decreases PDGF-BB-, EGF-, and bFGF-induced phosphorylation of PDGFR, EGFR, and FGFR1 in vitro; decreases serum-stimulated growth (IC50 = 1.8 µM after 8 days) and migration (IC50 = 4.5 µM) of rat aortic smooth muscle cells
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
