PARP (Cleaved) Monoclonal Antibody
CAY-13557-1 1 ea
Data Sheet: 
Applications
WB and FC (intracellular)
Source / Host
Mouse
Immunogen
synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP
IsoType
IgG2bκ
Formulation
100 µg protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
Shipment
-20
Long Term Storage
-20
Shelf Life
365
Description
Antigen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP • Isotype: IgG2bκ • Host: mouse • Cross Reactivity: (+) human PARP • Application(s): FC (intracellular) and WB • PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
