PAP-1
CAY-30105-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
870653-45-5
Formulation
A solid
Purity
≥98%
MW
350,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
PAP-1 is an inhibitor of Kv1.3 voltage-gated potassium channels (EC50 = 2 nM at -80 mV in cells overexpressing the human channel).{58913} It is selective for Kv1.3 over a panel of 22 ion channels, including potassium, sodium, calcium, and chloride channels (EC50s = 45-15,000 nM for all). PAP-1 inhibits anti-CD3 antibody-induced proliferation of isolated human CCR7- effector memory T cells. In vivo, PAP-1 (3 mg/kg) inhibits ovalbumin-induced delayed-type hypersensitivity in rats.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
