Nicaraven
CAY-23482-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
79455-30-4
Formulation
A crystalline solid
Purity
≥98%
MW
284,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Nicaraven is an antioxidant that exhibits hydroxyl radical scavenging activity in vitro.{36261} Nicaraven (1-3 mg/kg per min, i.v.) reduces occurrence of chronic cerebral vasospasms in a dose-dependent manner in a canine model of subarachnoid hemorrhage. In a canine model of warm hepatic ischemia and reperfusion injury, nicaraven (2 mg/kg per min, i.v.) reduces liver enzyme release and inhibits lipid peroxidation and neutrophil infiltration in the liver.{36262} Nicaraven (100 mg/kg per day, i.p.) also decreases plasma levels of the inflammatory cytokines Il-6 and Tnf-α and the urinary levels of 8-oxo-2'-deoxyguanosine, a marker of DNA oxidation, in a mouse model of radiation-induced injury.{36263}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
