
Reactivity
Human, Mouse, Rat
Applications
WB
Source / Host
Rabbit
Immunogen
A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
Purity
Protein A affinity chromatography
Long Term Storage
Aliquot and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Description
NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC (non-small cell lung cancer), suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).