CAS
7232-21-5
Formulation
A crystalline solid
Purity
≥98%
MW
336,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dual 5-HT3 and dopamine D2 receptor antagonist (IC50s = 308 and 483 nM, respectively); inhibits AChE isolated from the human postmortem caudate nucleus (Kis = 9.3 and 82 μM for competitive and non-competitive inhibition, respectively); oral administration inhibits emesis induced by cisplatin in ferrets (ED50 = 6,170 µg/kg) and apomorphine in dogs (ED50 = 0.45 mg/kg); inhibits apomorphine-induced climbing and stereotypy in mice (ED50s = 2.2 and 6.5 mg/kg, respectively)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).