
CAS
41179-33-3
Formulation
A crystalline solid
Purity
≥98%
MW
349,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A substrate-selective p38α MAPK inhibitor; selectively inhibits p38α-dependent phosphorylation of MK2 over ATF2 (Ki = 330 and >20,000 nM, respectively, in cell-free assays); inhibits proliferation of U87, A172, and U251 glioblastoma cells (EC50s = 0.6-1 μM) via inhibition of tubulin polymerization and induction of apoptosis
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).