MK-1064
CAY-20993-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
1207253-08-4
Formulation
A crystalline solid
Purity
≥98%
MW
461,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An OX2R antagonist; selective for OX2R over OX1R (IC50s = 18 and 1,789 nM, respectively); decreases the amount of time spent in active wake and increases the time spent in REM sleep and SMS in mice, rats, dogs, and rhesus monkeys at 100, 20, 1, and 10 mg/kg, respectively; inhibits restraint stress-induced increases in plasma ACTH levels and struggle behavior, as well as decreases in body weight, at 30 mg/kg in rats expressing the hM3Dq DREADD activated by CNO in orexin neurons
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
