MEDICA 16
CAY-90290-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
87272-20-6
Formulation
A crystalline solid
Purity
≥98%
MW
342,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A GPR40 agonist and GPR120 partial agonist; induces intracellular calcium mobilization in cells expressing GPR40 or GPR120; induces ERK activation in cells expressing GPR40 or GPR120 at 100 µM; inhibits ATP citrate lyase (Kis = 40 and 200 µM for the oxidized and reduced enzyme, respectively); chronic dietary administration of MEDICA 16 (0.25% w/w) decreases liver ACC and AMPK levels in a model of insulin resistance using JCR:LA-cp rats; reduces plasma insulin levels, decreases fasting plasma triacylglycerol levels, and delays the onset of hyperinsulinemia in JCR:LA-cp rats at 0.25% w/w in the diet
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
