CAS
2136247-12-4
Formulation
A solid
Purity
≥95%
MW
889,795663
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A PROTAC that drives MDM2 degradation; induces degradation of MDM2, which increases p53 levels, in RS4;11 cells at 10 nM; inhibits the growth of RS4;11 cells (IC50 = 1.5 nM); induces complete tumor regression and does not affect body weight in an RS4;11 mouse xenograft model at 50 mg/kg every other day for three weeks
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).